Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 2/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 5/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29520153 | 0.81 | PRKCI (0.58) | PRKCINAPRTP2RX7PIK3CDVCP | |
| SCHEMBL13973141 | 0.81 | PRKCI (0.58) | PRKCINAPRTP2RX7PIK3CDVCP | |
| SCHEMBL21185859 | 0.79 | KDM4E (0.57) | GAAACRKMT2A | |
| SCHEMBL11538362 | 0.79 | PRKCI (0.55) | PRKCINAPRTP2RX7VCPKMT2A | |
| SCHEMBL28765983 | 0.78 | PRKCI (0.58) | PRKCINAPRTP2RX7PIK3CDVCP | |
| SCHEMBL5674946 | 0.78 | ALDH1A1 (0.55) | ADORA2AADORA1ACR | |
| SCHEMBL18205768 | 0.78 | ALDH1A1 (0.55) | ADORA2AADORA1ACR | |
| SCHEMBL18205787 | 0.78 | ALDH1A1 (0.55) | ADORA2AADORA1ACR | |
| SCHEMBL11538360 | 0.78 | PRKCI (0.58) | PRKCINAPRTP2RX7VCPMAPT | |
| SCHEMBL26693008 | 0.77 | P2RX7 (0.66) | PRKCINAPRTP2RX7VCPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132950-A | Compounds and methods of use | 麦迪韦逊技术股份有限公司 | 2016-11-16 | — | — | CN | disclosed |