Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | AHCY | P23526 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.37 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.37 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADA | P00813 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665301 | 0.78 | ADORA2A (0.69) | ADORA2AADORA1EGFRSRCKDR | |
| SCHEMBL5801729 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1EGFRSRCKDR | |
| SCHEMBL11611616 | 0.77 | ADORA2A (0.51) | ADORA2AADORA1LMNAEGFRSRC | |
| SCHEMBL1665392 | 0.76 | ADORA2A (0.71) | ADORA2AADORA1EGFRSRCKDR | |
| SCHEMBL4815868 | 0.76 | ADORA2A (0.75) | ADORA2AADORA1LMNASMN1; SMN2ADORA2B | |
| SCHEMBL4815870 | 0.76 | ADORA2A (0.71) | ADORA2AADORA1LMNAEGFRSRC | |
| SCHEMBL5810639 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BAHCYALDH1A1 | |
| SCHEMBL29496348 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BAHCYALDH1A1 | |
| SCHEMBL1393316 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BAHCYALDH1A1 | |
| SCHEMBL904363 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BAHCYALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108358968-B | Preparation method of tenofovir | 科兴生物制药股份有限公司 | 2020-09-15 | — | — | CN | disclosed |
| CN-108358968-A | A kind of preparation method of high-purity tenofovir | 山东科兴生物制品有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-104230934-B | A kind of compound and its production and use | 上海医药工业研究院 | 2016-12-28 | — | — | CN | disclosed |