Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280835 | 0.83 | HTT (0.43) | HTTKMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL15567082 | 0.82 | KMT2A (0.46) | HTTKMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28116189 | 0.81 | KMT2A (0.51) | HTTKMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28115800 | 0.81 | LMNA (0.52) | HTTKMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL28116184 | 0.81 | KMT2A (0.44) | HTTKMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL163578 | 0.81 | ALDH1A1 (0.50) | HTTKMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL8770703 | 0.80 | HTT (0.63) | HTTKMT2AALDH1A1HSD17B10GAA | |
| Bicarbonate SCHEMBL27510048 | 0.79 | ALDH1A1 (0.49) | HTTKMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL2788102 | 0.79 | ALDH1A1 (0.49) | HTTKMT2AMAPTALDH1A1HSD17B10 | |
| SCHEMBL9243414 | 0.79 | HTT (0.47) | HTTKMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001070-B | Synthesis method for beta-hydroxy-ketone compound | 浙江工业大学 | 2017-01-18 | — | — | CN | disclosed |