SCHEMBL9280835

SCHEMBL9280835

C=CCC(=O)Oc1ccc(O)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.43
KMT2A Q03164 4/20 0.41
MAPT P10636 3/20 0.41
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
HSD17B10 Q99714 1/20 0.41
PARP10 Q53GL7 1/20 0.40
ELANE P08246 2/20 0.40
ALDH5A1 P51649 1/20 0.39
ABAT P80404 1/20 0.39
GAA P10253 3/20 0.39
THRB P10828 3/20 0.39
XBP1 P17861 1/20 0.39
ESR1 P03372 3/20 0.38
MEN1 O00255 1/20 0.38
ESR2 Q92731 1/20 0.38
HIF1A Q16665 2/20 0.38
RECQL P46063 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9283080 0.95 ESR2 (0.41) HTTKMT2AMAPTALDH1A1LMNA
SCHEMBL8943480 0.89 APP (0.50) HTTKMT2AMAPTLMNAPARP10
SCHEMBL28116189 0.83 KMT2A (0.51) HTTKMT2AMAPTALDH1A1LMNA
SCHEMBL28115799 0.83 HTT (0.42) HTTKMT2AMAPTALDH1A1LMNA
SCHEMBL28116184 0.83 KMT2A (0.44) HTTKMT2AMAPTALDH1A1LMNA
SCHEMBL28115800 0.83 LMNA (0.52) HTTKMT2AMAPTALDH1A1LMNA
SCHEMBL163578 0.82 ALDH1A1 (0.50) HTTKMT2AMAPTALDH1A1HSD17B10
SCHEMBL8770703 0.81 HTT (0.63) HTTKMT2AALDH1A1HSD17B10PARP10
SCHEMBL2788102 0.81 ALDH1A1 (0.49) HTTKMT2AMAPTALDH1A1HSD17B10
SCHEMBL17183797 0.81 MEN1 (0.38) HTTKMT2AMAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108136073-A Engineered stent including particle egg shell membrane 生物科技有限公司 2018-06-08 CN disclosed
US-9890417-B2 Signal amplification of fluorescence in situ hybridization AGILENT TECHNOLOGIES, INC. (US) 2018-02-13 US disclosed
CN-107106733-A Micronized eggshell membrane particles and their use to promote wound healing 生物科技有限公司 2017-08-29 CN disclosed
WO-2016073350-A1 SIGNAL AMPLIFICATION OF FLUORESCENCE IN SITU HYBRIDIZATION AGILENT TECHNOLOGIES, INC. (US) 2016-05-12 WO disclosed
US-20160122800-A1 SIGNAL AMPLIFICATION OF FLUORESCENCE IN SITU HYBRIDIZATION AGILENT TECHNOLOGIES, INC. 2016-05-05 US disclosed
US-5385693-A Having rapid response and low phase transition temperature SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-31 US disclosed
US-5374376-A Optically active aromatic compounds, preparation process therefor, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-12-20 US disclosed
EP-0357372-B1 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL CO (JP) 1994-11-17 EP disclosed
EP-0357435-B1 Optically active aromatic compounds, preparation process therefor, liquid crystal materials and a light switching element SUMITOMO CHEMICAL CO (JP) 1993-12-08 EP disclosed
US-5264151-A Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-23 US disclosed
US-5238598-A Having trifluoromethyl group; high speed response SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-24 US disclosed
US-5124070-A High speed response SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-06-23 US disclosed
EP-0434297-A2 Optically active aromatic compounds, preparation process thereof, and liquid crystal compositions and elements SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-06-26 EP disclosed
EP-0357372-A2 Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed
EP-0357435-A2 Optically active aromatic compounds, preparation process therefor, liquid crystal materials and a light switching element SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-03-07 EP disclosed