Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9280835 | 0.83 | HTT (0.43) | LMNAGAAKMT2ATDP1HTT | |
| SCHEMBL12641470 | 0.83 | LMNA (0.53) | LMNAGAAKMT2AL3MBTL1TDP1 | |
| SCHEMBL27367109 | 0.82 | KMT2A (0.54) | LMNAGAAKMT2AL3MBTL1TDP1 | |
| SCHEMBL28116189 | 0.81 | KMT2A (0.51) | LMNAGAAKMT2AHTTHPGD | |
| SCHEMBL28116184 | 0.81 | KMT2A (0.44) | LMNAGAAKMT2ATDP1HTT | |
| SCHEMBL28115799 | 0.81 | HTT (0.42) | LMNAGAAKMT2AHTTALDH1A1 | |
| SCHEMBL163578 | 0.81 | ALDH1A1 (0.50) | GAAKMT2AL3MBTL1TDP1HTT | |
| Acetic Acid SCHEMBL27635072 | 0.80 | ALDH1A1 (0.47) | LMNAGAAKMT2ATDP1HTT | |
| SCHEMBL8770703 | 0.80 | HTT (0.63) | GAAKMT2AL3MBTL1HTTALDH1A1 | |
| SCHEMBL2788102 | 0.79 | ALDH1A1 (0.49) | GAAKMT2AL3MBTL1TDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001070-B | Synthesis method for beta-hydroxy-ketone compound | 浙江工业大学 | 2017-01-18 | — | — | CN | disclosed |