Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 5/20 | 0.48 |
| ▸ | RHOA | P61586 | 5/20 | 0.48 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.42 |
| ▸ | VNN1 | O95497 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28000419 | 0.91 | RHOC (0.52) | RHOCRHOADDR1ALDH1A1POLB | |
| SCHEMBL13753113 | 0.85 | ALDH1A1 (0.65) | RHOCRHOADDR1ALDH1A1POLB | |
| SCHEMBL13753001 | 0.81 | DDR1 (0.55) | RHOCRHOADDR1ALDH1A1POLB | |
| SCHEMBL615458 | 0.80 | TACR1 (0.50) | RHOCRHOADDR1TACR1MLYCD | |
| SCHEMBL14528862 | 0.79 | RHOC (0.48) | RHOCRHOADDR1ALDH1A1POLB | |
| SCHEMBL27791536 | 0.77 | MEN1 (0.63) | ALDH1A1HDAC3HDAC1HDAC2HDAC6 | |
| Hydrochloric Acid SCHEMBL27791610 | 0.76 | MEN1 (0.62) | ALDH1A1POLB | |
| SCHEMBL14214023 | 0.76 | CES2 (0.47) | DDR1TACR1RXFP1VNN1GAA | |
| SCHEMBL25757925 | 0.76 | CES2 (0.47) | RHOCRHOADDR1TACR1VNN1 | |
| SCHEMBL14430729 | 0.75 | KMT2A (0.54) | RHOCRHOAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104496962-B | A kind of Oligopoly thiophene derivative and application thereof | 南方医科大学 | 2017-01-04 | — | — | CN | disclosed |
| CN-104496962-A | Oligothiophene derivative and application thereof | UNIV SOUTHERN MEDICAL | 2015-04-08 | — | — | CN | disclosed |