Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL28098260 | 0.89 | FFAR3 (0.42) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Succinic Acid SCHEMBL28071063 | 0.84 | LMNA (0.53) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL27260868 | 0.82 | LMNA (0.56) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL28899790 | 0.82 | LMNA (0.56) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL7567030 | 0.82 | LMNA (0.56) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL30298887 | 0.79 | LMNA (0.53) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL18839954 | 0.79 | LMNA (0.60) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL155053 | 0.79 | LMNA (0.60) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL11154339 | 0.79 | LMNA (0.60) | EGLN1LMNAALKBH5SUCNR1MAPK1 | |
| Succinic Acid SCHEMBL151456 | 0.79 | LMNA (0.60) | EGLN1LMNAALKBH5SUCNR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106187828-A | Alkylbenzene methanol polyoxyethylene ether disodium succinate salt and preparation method thereof | 南通市晗泰化工有限公司 | 2016-12-07 | — | — | CN | disclosed |