Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17251750 | 0.76 | MAPT (0.50) | KDM4EHPGDHSD17B10MAPTTP53 | |
| SCHEMBL28116288 | 0.76 | PARP1 (0.53) | USP2MAPTTP53GUSBPARP1 | |
| SCHEMBL16017996 | 0.73 | GUSB (0.76) | GUSBCDK4CCND1PARP1KMT2A | |
| SCHEMBL7917574 | 0.73 | ALDH1A1 (0.61) | KDM4EHPGDUSP2GAAHSD17B10 | |
| SCHEMBL28116286 | 0.72 | MAPT (0.43) | KDM4EHPGDGAAHSD17B10MAPT | |
| SCHEMBL28027631 | 0.70 | TNKS (0.54) | KDM4EHPGDGAAHSD17B10TP53 | |
| SCHEMBL28116661 | 0.70 | PARP1 (0.48) | KDM4EUSP2GAAMAPTTP53 | |
| SCHEMBL8715864 | 0.69 | HTR6 (0.74) | KDM4EHPGDUSP2GAAHSD17B10 | |
| SCHEMBL16638382 | 0.69 | DHODH (0.70) | KDM4EHPGDMAPTGUSBPARP1 | |
| SCHEMBL28116302 | 0.69 | CHEK2 (0.42) | KDM4EHPGDGAAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104072425-B | Benzimidazole compound and application thereof | 大连理工大学 | 2016-12-07 | — | — | CN | disclosed |