Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116674 | 0.88 | RIPK1 (0.46) | KMT2APKMMEN1LMNAPTGER1 | |
| SCHEMBL28269332 | 0.83 | KMT2A (0.51) | KMT2APKMMEN1LMNASMN1; SMN2 | |
| SCHEMBL1865930 | 0.81 | LMNA (0.47) | KMT2APKMMEN1LMNASMN1; SMN2 | |
| SCHEMBL1861055 | 0.79 | NPC1 (0.47) | KMT2APKMMEN1LMNASMN1; SMN2 | |
| SCHEMBL28116788 | 0.78 | LMNA (0.55) | KMT2APKMMEN1LMNASMN1; SMN2 | |
| SCHEMBL765196 | 0.78 | PTGER1 (0.68) | PTGER1 | |
| SCHEMBL28116367 | 0.78 | RECQL (0.52) | KMT2APKMLMNASMN1; SMN2KDM4E | |
| SCHEMBL17316603 | 0.76 | HDAC1 (0.49) | KMT2APKMMEN1LMNASMN1; SMN2 | |
| SCHEMBL17316539 | 0.76 | LMNA (0.44) | KMT2APKMMEN1LMNASMN1; SMN2 | |
| SCHEMBL28116296 | 0.75 | RIPK1 (0.60) | KMT2APKMMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669558-B | Benzyl -1H- pyrazoles, benzyl -1H- azole derivatives and its preparation method and application | 四川大学 | 2019-01-22 | — | — | CN | disclosed |
| CN-106146400-A | Benzyl-1H-pyrazoles, benzyl-1H-azole derivatives and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |