Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ARNT | P27540 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116300 | 0.86 | HDAC1 (0.47) | LMNAALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28116296 | 0.84 | RIPK1 (0.60) | LMNAALDH1A1KMT2ARIPK1POLB | |
| SCHEMBL28269332 | 0.81 | KMT2A (0.51) | LMNAALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL21199265 | 0.80 | SOS1 (0.52) | LMNAALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL28116674 | 0.80 | RIPK1 (0.46) | LMNAALDH1A1KMT2ARIPK1POLB | |
| SCHEMBL28116675 | 0.78 | KMT2A (0.45) | LMNAALDH1A1SMN1; SMN2KMT2APOLB | |
| SCHEMBL17316539 | 0.76 | LMNA (0.44) | LMNAALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL17316603 | 0.76 | HDAC1 (0.49) | LMNAALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL3440031 | 0.76 | L3MBTL1 (0.56) | LMNAALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL28116676 | 0.76 | PKM (0.44) | LMNAALDH1A1L3MBTL1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146400-A | Benzyl-1H-pyrazoles, benzyl-1H-azole derivatives and its production and use | 四川大学 | 2016-11-23 | — | — | CN | disclosed |