Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632003 | 0.90 | PGR (0.40) | ADRA1DADRA1AADRA1BPGR | |
| SCHEMBL28287348 | 0.83 | HSP90AA1 (0.37) | NPC1RAB9AMAPTKDM4EADRA1D | |
| SCHEMBL1929731 | 0.83 | TDP2 (0.33) | PGRTDP2 | |
| Fluorene SCHEMBL28871819 | 0.80 | PGR (0.36) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL30511096 | 0.76 | PGR (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL88451 | 0.76 | PGR (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL1928517 | 0.75 | PDK2 (0.33) | — | |
| SCHEMBL481172 | 0.74 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL30561571 | 0.74 | ALDH1A1 (0.59) | ALDH1A1NPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL1926840 | 0.73 | TGM2 (0.35) | PGRTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106220553-A | Carbazole-fluorene ethylene derivatives and synthetic method thereof | 沈阳大学 | 2016-12-14 | — | — | CN | claimed |
| CN-106220553-A | Carbazole-fluorene ethylene derivatives and synthetic method thereof | 沈阳大学 | 2016-12-14 | — | — | CN | disclosed |