Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3856071 | 0.82 | NPSR1 (0.30) | NPSR1 | |
| SCHEMBL3856069 | 0.80 | NPSR1 (0.31) | NPSR1ALDH1A1 | |
| SCHEMBL5831274 | 0.78 | ALDH1A1 (0.33) | NPSR1IMPDH2ALDH1A1HPGD | |
| SCHEMBL456738 | 0.70 | — | — | |
| SCHEMBL11812461 | 0.70 | MAPK1 (0.40) | NPSR1ALDH1A1HPGD | |
| SCHEMBL9621343 | 0.69 | XDH (0.31) | NPSR1ALDH1A1HPGD | |
| SCHEMBL5449547 | 0.67 | IMPDH2 (0.31) | IMPDH2 | |
| SCHEMBL17961910 | 0.67 | — | — | |
| SCHEMBL5819477 | 0.67 | — | — | |
| SCHEMBL5465101 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217814-B2 | Methods of producing phosphitylated compounds | HONEYWELL INTERNATIONAL INC. (US) | 2007-05-15 | — | — | US | disclosed |
| US-20050124804-A1 | Methods of producing phosphitylated compounds | WERNER CHRISTIAN (DE) | 2005-06-09 | — | — | US | disclosed |
| US-6894158-B2 | Methods of producing phosphitylated compounds | HONEYWELL INTERNATIONAL INC. (US) | 2005-05-17 | — | — | US | disclosed |
| EP-1476407-A2 | METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS | Honeywell International Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| US-20030232980-A1 | Methods of producing phosphitylated compounds | HONEYWELL INTERNATIONAL INC. | 2003-12-18 | — | — | US | disclosed |
| WO-2003072586-A2 | METHODS OF PRODUCING PHOSPHITYLATED COMPOUNDS | HONEYWELL INTERNATIONAL INC. (US) | 2003-09-04 | — | — | WO | disclosed |
| EP-0220204-A1 | THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
| WO-1986006386-A1 | THERMOSETTABLE POLYSTYRYLPYRIDINE PREPOLYMER TERMINATED WITH ETHYLENICALLY UNSATURATED GROUPS AND CURED PRODUCTS THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1986-11-06 | — | — | WO | disclosed |
| US-4575542-A | Thermosettable polystyrylpyridine prepolymer terminated with ethylenically unsaturated groups and cured products therefrom | THE DOW CHEMICAL COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050124804-A1 | Methods of producing phosphitylated compounds | PHOSPHO1, INPPL1, PLCB3 | NPSR1 1488/4885IMPDH2 2442/4885ALDH1A1 4296/4885 |
| US-20030232980-A1 | Methods of producing phosphitylated compounds | PHOSPHO1, INPPL1, PLCG1 | NPSR1 2746/4885IMPDH2 2609/4885ALDH1A1 3089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.