SCHEMBL28117586

SCHEMBL28117586

CSc1ccccc1S(=O)(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.44
ALDH1A1 P00352 4/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 1/20 0.40
TSHR P16473 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
KMT2A Q03164 3/20 0.39
TTR P02766 1/20 0.38
MEN1 O00255 1/20 0.38
PTGES2 Q9H7Z7 1/20 0.38
HPGD P15428 1/20 0.37
MAPT P10636 1/20 0.37
NPSR1 Q6W5P4 2/20 0.36
SLC2A1 P11166 1/20 0.36
GAA P10253 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21084687 0.82 MYC (0.42) MYCALDH1A1SMN1; SMN2TSHRCA12
SCHEMBL8450545 0.80 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2HTTCA12CA1
SCHEMBL2226182 0.78 CA2 (0.56) ALDH1A1SMN1; SMN2CA12CA1CA2
SCHEMBL514775 0.78 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2HTTCA12CA1
SCHEMBL27989888 0.78 MYC (0.40) MYCALDH1A1SMN1; SMN2TSHRCA12
SCHEMBL5533557 0.78 MYC (0.40) MYCALDH1A1SMN1; SMN2TSHRCA12
SCHEMBL1501079 0.78 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2HTTCA12CA1
SCHEMBL3794933 0.78 MYC (0.41) MYCALDH1A1SMN1; SMN2HTTTSHR
SCHEMBL25464041 0.77 PSIP1 (0.45) ALDH1A1SMN1; SMN2HTTCA12CA1
SCHEMBL9492408 0.77 CA2 (0.55) ALDH1A1SMN1; SMN2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116715615-A Synthesis method of o-deuterated methylthio diarylamine compound 温州医科大学 2023-09-08 CN disclosed
CN-116715614-A Synthetic method of alkenyl deuterated methyl sulfide compound 温州医科大学 2023-09-08 CN disclosed
CN-106278965-A Aryl alkyl asymmetric over cure compounds and synthetic method thereof and application 华东师范大学 2017-01-04 CN disclosed