Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.55 |
| ▸ | CA9 | Q16790 | 10/20 | 0.55 |
| ▸ | CA1 | P00915 | 9/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.55 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 4/20 | 0.48 |
| ▸ | CA5A | P35218 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226182 | 0.98 | CA2 (0.56) | CA2CA9CA1CA12CA14 | |
| SCHEMBL6823501 | 0.82 | PTGES2 (0.47) | CA2CA9CA1CA12CA14 | |
| SCHEMBL9269411 | 0.80 | CA2 (0.54) | CA2CA9CA1CA12CA14 | |
| SCHEMBL9819445 | 0.80 | CA2 (0.47) | CA2CA9CA1CA12CA14 | |
| SCHEMBL8450545 | 0.78 | ALDH1A1 (0.44) | CA2CA9CA1CA12CA14 | |
| SCHEMBL28117586 | 0.77 | MYC (0.44) | CA2CA9CA1CA12CA14 | |
| SCHEMBL1501079 | 0.77 | ALDH1A1 (0.43) | CA2CA9CA1CA12CA14 | |
| SCHEMBL514775 | 0.77 | ALDH1A1 (0.43) | CA2CA9CA1CA12CA14 | |
| SCHEMBL7545831 | 0.76 | ALOX15 (0.46) | CA2CA9CA1CA12CA14 | |
| SCHEMBL10567717 | 0.76 | CA2 (0.45) | CA2CA9CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270313-A | Treatment of circulatory disorders | HOFFMANN-LA ROCHE INC. (US) | 1993-12-14 | — | — | US | disclosed |