Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18420898 | 1.00 | KCNK3 (0.41) | KCNK3DRD2DRD3PTGDR2MAPK1 | |
| SCHEMBL17574594 | 0.81 | SETD7 (0.40) | KCNK3DRD2DRD3PDK1PDK2 | |
| SCHEMBL17574595 | 0.81 | SETD7 (0.40) | KCNK3DRD2DRD3PDK1PDK2 | |
| SCHEMBL13662624 | 0.80 | P2RX7 (0.42) | DRD2DRD3PTGDR2MAPK1 | |
| SCHEMBL3462061 | 0.80 | MAPK1 (0.50) | DRD2DRD3PTGDR2MAPK1HSD11B1 | |
| SCHEMBL22117940 | 0.80 | MAPK1 (0.50) | DRD2DRD3PTGDR2MAPK1HSD11B1 | |
| SCHEMBL21772146 | 0.80 | MAPK1 (0.50) | DRD2DRD3PTGDR2MAPK1HSD11B1 | |
| SCHEMBL1393516 | 0.79 | ALOX15 (0.40) | DRD2DRD3PTGDR2MAPK1CHRM4 | |
| SCHEMBL13658785 | 0.76 | DRD2 (0.34) | DRD2DRD3PTGDR2HSD11B1PDK1 | |
| SCHEMBL13733481 | 0.75 | HSD17B10 (0.37) | DRD2DRD3PTGDR2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169281-B | The pyrroles's diformamide condensed and they are as the purposes of medicine | 赛诺菲 | 2016-12-14 | — | — | CN | disclosed |