Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2203957 | 0.79 | MGAM (0.47) | ALDH1A1ABCB1SMN1; SMN2MGAMGAA | |
| SCHEMBL28332085 | 0.74 | MGAM (0.46) | HSD17B10KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL28306752 | 0.73 | ALDH1A1 (0.48) | HSD17B10KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL8843535 | 0.72 | PDE4A (0.63) | HSD17B10KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL19831010 | 0.71 | SMPD1 (0.59) | HSD17B10KDM4EALDH1A1LMNAABCB1 | |
| SCHEMBL12303132 | 0.71 | KDM4E (0.60) | HSD17B10KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL28321999 | 0.71 | TUBB4A (0.44) | ALDH1A1KMT2A | |
| SCHEMBL27542138 | 0.71 | SMPD1 (0.59) | HSD17B10KDM4EALDH1A1LMNAABCB1 | |
| SCHEMBL8844461 | 0.71 | HSD17B10 (0.48) | HSD17B10KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL4411377 | 0.70 | PDCD1 (0.76) | HDAC1HDAC8HDAC6PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110240539-A | A kind of fluorine substituted diphenylamine ethane compound and preparation method and application | 上海应用技术大学 | 2019-09-17 | — | — | CN | disclosed |
| CN-106279058-B | The preparation and purposes of 3,4- diaryl -1,2,5- oxadiazoles oxide | 沈阳药科大学 | 2019-07-26 | — | — | CN | disclosed |
| CN-106279058-A | The preparation of 3,4-diaryl-1,2,5-diazole oxide and purposes | 沈阳药科大学 | 2017-01-04 | — | — | CN | disclosed |