Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SI | P14410 | 2/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8843535 | 0.78 | PDE4A (0.63) | HSD17B10KDM4EALDH1A1TSHRUSP2 | |
| SCHEMBL8843771 | 0.77 | PDE4A (0.52) | HSD17B10KDM4EALDH1A1TSHRUSP2 | |
| SCHEMBL4167435 | 0.75 | ABCG2 (0.70) | HSD17B10KDM4EALDH1A1TSHRLMNA | |
| SCHEMBL8844119 | 0.74 | KDM4E (0.67) | HSD17B10KDM4EALDH1A1TSHRUSP2 | |
| SCHEMBL31675780 | 0.74 | TUBB4A (0.70) | HSD17B10KDM4ECYP1A1CYP1A2MAPT | |
| SCHEMBL4649099 | 0.74 | TUBB4A (0.70) | HSD17B10KDM4ECYP1A1CYP1A2MAPT | |
| SCHEMBL28306752 | 0.73 | ALDH1A1 (0.48) | HSD17B10KDM4EALDH1A1TSHRUSP2 | |
| SCHEMBL7545480 | 0.73 | PPARG (0.70) | KDM4EALDH1A1CYP1A1CYP1A2ABCG2 | |
| SCHEMBL8581527 | 0.72 | PDE4A (0.63) | HSD17B10KDM4EALDH1A1TSHRUSP2 | |
| SCHEMBL8843865 | 0.72 | F2 (0.49) | KDM4EALDH1A1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629340-A | DIPHENYL FURAN COMPOUNDS | TSUMURA & CO. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0678296-A1 | VASCULARIZATION INHIBITOR AND NOVEL COMPOUND | TSUMURA & CO. (JP) | 1995-10-25 | — | — | EP | disclosed |