Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 10/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | MPL | P40238 | 2/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27642819 | 0.85 | KIF11 (0.54) | KIF11KCNH2 | |
| SCHEMBL10299815 | 0.80 | KIF11 (0.58) | KIF11ARAPPMPL | |
| SCHEMBL67628 | 0.80 | KIF11 (0.58) | KIF11ARAPPMPL | |
| SCHEMBL22925065 | 0.79 | NPFFR1 (0.37) | KIF11ARCTSSCTSKAPP | |
| SCHEMBL16960400 | 0.77 | NFE2L2 (0.52) | — | |
| SCHEMBL29110066 | 0.77 | APP (0.42) | KIF11ARAPPMPL | |
| SCHEMBL29110062 | 0.77 | APP (0.42) | KIF11ARAPPMPL | |
| SCHEMBL13358948 | 0.76 | NR3C2 (0.40) | KIF11ARAPP | |
| SCHEMBL398398 | 0.76 | KIF11 (0.41) | KIF11ARAPPMPLHTR2A | |
| SCHEMBL21236969 | 0.76 | NPFFR1 (0.40) | KIF11ARAPPMPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169281-B | The pyrroles's diformamide condensed and they are as the purposes of medicine | 赛诺菲 | 2016-12-14 | — | — | CN | claimed |
| CN-104169281-B | The pyrroles's diformamide condensed and they are as the purposes of medicine | 赛诺菲 | 2016-12-14 | — | — | CN | disclosed |