Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 9/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21236969 | 0.81 | NPFFR1 (0.40) | NPFFR1NPFFR2ARKIF11L3MBTL1 | |
| SCHEMBL28117960 | 0.79 | KIF11 (0.42) | ARKIF11CTSSCTSKAPP | |
| SCHEMBL2447369 | 0.77 | NPFFR1 (0.43) | NPFFR1NPFFR2ARKIF11L3MBTL1 | |
| SCHEMBL2447368 | 0.77 | NPFFR1 (0.43) | NPFFR1NPFFR2ARKIF11L3MBTL1 | |
| SCHEMBL22925145 | 0.77 | ALDH1A1 (0.41) | NPFFR1NPFFR2ARKIF11L3MBTL1 | |
| SCHEMBL25622482 | 0.72 | NPFFR1 (0.34) | NPFFR1NPFFR2ARKIF11L3MBTL1 | |
| SCHEMBL25753392 | 0.72 | NPFFR1 (0.34) | NPFFR1NPFFR2ARKIF11L3MBTL1 | |
| SCHEMBL29110062 | 0.72 | APP (0.42) | ARKIF11L3MBTL1APPCYP3A4 | |
| SCHEMBL29110066 | 0.72 | APP (0.42) | ARKIF11L3MBTL1APPCYP3A4 | |
| SCHEMBL16993678 | 0.71 | NPFFR2 (0.71) | NPFFR1NPFFR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021012264-A1 | TRIAZOLE SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 东莞市东阳光农药研发有限公司 | 2021-01-28 | — | — | WO | disclosed |