Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28230871 | 0.90 | ALDH1A1 (0.48) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL28118618 | 0.88 | AR (0.43) | KMT2AALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL18381542 | 0.88 | VCAM1 (0.50) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL29441730 | 0.88 | VCAM1 (0.50) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL17080189 | 0.86 | HCAR3 (0.58) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL18666979 | 0.79 | HCAR3 (0.50) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL17085960 | 0.76 | POLB (0.49) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL29441709 | 0.76 | POLB (0.49) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL17080210 | 0.75 | HCAR3 (0.50) | KMT2AALDH1A1SMN1; SMN2MEN1MAPT | |
| SCHEMBL16953241 | 0.75 | SIRT6 (0.46) | KMT2AALDH1A1MEN1KDM4EPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110437153-A | hepatitis B core protein allosteric modulators | UNIV INDIANA RES & TECH CORP | 2019-11-12 | — | — | CN | disclosed |
| CN-106413402-A | Hepatitis b core protein allosteric modulators | 美国印第安纳大学研究和技术公司 | 2017-02-15 | — | — | CN | disclosed |