Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.83 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.74 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.34 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.31 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiouracil SCHEMBL9172 | 0.91 | — | — | |
| Thiouracil SCHEMBL30091289 | 0.89 | — | — | |
| Thiouracil SCHEMBL27922231 | 0.89 | — | — | |
| Uracil SCHEMBL28946101 | 0.86 | CRBN (0.90) | TP53CRBNMMP2SMN1; SMN2TYMP | |
| Uracil SCHEMBL3798527 | 0.86 | CRBN (1.00) | TP53CRBNMMP2SMN1; SMN2TYMP | |
| Uracil SCHEMBL8235 | 0.86 | — | — | |
| Uracil SCHEMBL5089507 | 0.86 | — | — | |
| Thiouracil SCHEMBL7804101 | 0.85 | TP53 (0.79) | TP53CRBNMMP2SMN1; SMN2LPO | |
| Uracil SCHEMBL8767625 | 0.84 | — | — | |
| Uracil SCHEMBL2161716 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107250148-A | Guide RNA with chemical modification | 安捷伦科技有限公司 | 2017-10-13 | — | — | CN | claimed |
| CN-112996504-A | Methods of treating cancer by inhibiting ubiquitin conjugating enzyme E2K (UBE2K) | 博格有限责任公司 | 2021-06-18 | — | — | CN | disclosed |
| CN-110520540-A | Nucleic acid modification and identification methods | IMBA INST FUR MOLEKULARE BIOTECHNOLOGIE GMBH | 2019-11-29 | — | — | CN | disclosed |
| CN-104053777-B | Nucleic acid fragment binding to target protein | 塔古西库斯生物株式会社 | 2016-12-07 | — | — | CN | disclosed |