⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiouracil SCHEMBL27922231 | 0.97 | — | — | |
| Thiouracil SCHEMBL30091289 | 0.97 | — | — | |
| Uracil SCHEMBL28120281 | 0.91 | TP53 (0.83) | — | |
| Thiouracil SCHEMBL7804101 | 0.89 | TP53 (0.79) | — | |
| Thiouracil SCHEMBL27970384 | 0.87 | TP53 (0.76) | — | |
| Thiouracil SCHEMBL28095966 | 0.87 | TP53 (0.76) | — | |
| Thiouracil SCHEMBL28205719 | 0.85 | TP53 (0.73) | — | |
| Thiouracil SCHEMBL4958659 | 0.81 | TP53 (0.66) | — | |
| Thiouracil SCHEMBL22345877 | 0.80 | TP53 (0.63) | — | |
| Uracil SCHEMBL28946101 | 0.74 | CRBN (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 48652 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026106497-A2 | FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION | SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) | 2026-05-21 | — | — | WO | claimed |
| US-12630827-B2 | Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies | ROGCON, INC. (US) | 2026-05-19 | — | — | US | claimed |
| CN-122029176-A | Containing a plurality of oligonucleotides modified oligonucleotides | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122029177-A | Oligonucleotides containing multiple ligands and/or lipids | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| CN-122028913-A | Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions | 阿达尔克斯制药有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-20260117214-A1 | Prime Editing Systems having pegRNA with Reduced Auto-inhibitory Interaction | UNIV MASSACHUSETTS (US) | 2026-04-30 | — | — | US | claimed |
| US-20260109977-A1 | MODIFIED RNA FOR INCREASING PROTEIN EXPRESSION | TRILINK BIOTECHNOLOGIES, LLC (US) | 2026-04-23 | — | — | US | claimed |
| US-12595486-B2 | Aptamers for personal health care applications | THE PROCTER & GAMBLE COMPANY (US) | 2026-04-07 | — | — | US | claimed |
| US-12596118-B2 | Oligonucleotides for inducing paternal UBE3A expression | HOFFMANN-LA ROCHE INC. (US) | 2026-04-07 | — | — | US | claimed |
| US-12584136-B2 | Aptamers for personal health care applications | THE PROCTER & GAMBLE COMPANY (US) | 2026-03-24 | — | — | US | claimed |
| EP-0118536-A1 | PAIN RELIEVING THERAPEUTIC COMPOSITION | THE BETH ISRAEL HOSPITAL ASSOCIATION (US) | 1984-09-19 | — | — | EP | claimed |
| WO-1984000887-A1 | PAIN RELIEVING THERAPEUTIC COMPOSITION | BETH ISRAEL HOSPITAL (US) | 1984-03-15 | — | — | WO | claimed |
| EP-0098122-A2 | Processes for producing L-proline by fermentation | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1984-01-11 | — | — | EP | claimed |
| US-4307187-A | THIOSULFONIC ACIDS PREVENT HEAT FOG WHEN STORED, REDUCING AGENTS | FUJI PHOTO FILM CO., LTD. (JP) | 1981-12-22 | — | — | US | claimed |
| EP-0038541-A1 | Novel prodrugs of biologically active agents containing mercapto groups, process for preparing and therapeutically effective composition containing the same | MERCK & CO. INC. (US) | 1981-10-28 | — | — | EP | claimed |
| US-4220709-A | Heat developable imaging materials and process | EASTMAN KODAK COMPANY (US) | 1980-09-02 | — | — | US | claimed |
| US-4196073-A | Hydrophilic thio compounds as selective depressants in the flotation separation of copper and molybdenum | CANADIAN INDUSTRIES LIMITED (CA) | 1980-04-01 | — | — | US | claimed |
| US-4096091-A | Limulus lysate having improved capacity to precipitate in the presence of low endotoxin concentrations, and reconstituting solutions therefor | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1978-06-20 | — | — | US | claimed |
| US-4088751-A | SHAVING CREAM, SHAMPOO, LOTION, 2-THIO-4-OXYPYRIMIDINE OR THIOHYDANTOIN AND HYDROGEN PEROXIDE, EXOTHERMIC REDOX REACTION | COLGATE-PALMOLIVE COMPANY (US) | 1978-05-09 | — | — | US | claimed |
| US-4002479-A | ORGANIC SILVER SALT, SILVER HALIDE, AND A REDUCING AGENT | FUJI PHOTO FILM CO., LTD. (JA) | 1977-01-11 | — | — | US | claimed |