Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 1.00 |
| ▸ | TGM2 | P21980 | 9/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716604 | 1.00 | CES1 (1.00) | CES1TGM2NSD2BCHEDAO | |
| Nitrogen SCHEMBL29242307 | 0.96 | CES1 (0.92) | CES1TGM2NSD2BCHEDAO | |
| SCHEMBL5740595 | 0.76 | CES1 (0.61) | CES1TGM2PBRM1 | |
| SCHEMBL9835981 | 0.76 | CES1 (0.61) | CES1TGM2PBRM1 | |
| SCHEMBL11543833 | 0.76 | CES1 (0.61) | CES1TGM2PBRM1 | |
| SCHEMBL2136384 | 0.75 | CES1 (0.60) | CES1DAOMAOAMAOBPBRM1 | |
| SCHEMBL4242823 | 0.75 | CES1 (0.60) | CES1TGM2MAOAMAOBPBRM1 | |
| SCHEMBL281203 | 0.75 | CES1 (0.60) | CES1TGM2BCHEMAOAMAOB | |
| SCHEMBL2838571 | 0.75 | CES1 (0.60) | CES1TGM2NSD2BCHEDAO | |
| SCHEMBL734955 | 0.75 | CES1 (1.00) | CES1TGM2NSD2BCHEDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119874711-A | Synthesis method and application of 1, 7-dichloroindolo [2,1-b ] quinazoline-6, 12-dione compound | 合肥工业大学 | 2025-04-25 | — | — | CN | claimed |
| CN-119684105-A | N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method | 贵州医科大学 | 2025-03-25 | — | — | CN | claimed |
| CN-113912609-B | Preparation method of natural alkaloid tryptanthrin and derivatives thereof | 江苏大学 | 2024-01-05 | — | — | CN | claimed |
| CN-113912609-A | Preparation method of natural alkaloid tryptanthrin and derivative thereof | 江苏大学 | 2022-01-11 | — | — | CN | claimed |
| CN-111574426-A | Diamine monomer containing isoindigo structure and black polyimide synthesized from diamine monomer | 湘潭大学 | 2020-08-25 | — | — | CN | claimed |
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | L'OREAL S.A. | 2007-06-14 | — | — | US | claimed |
| US-7204857-B1 | Dyeing method using a specific active methylene compound and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL S.A. (FR) | 2007-04-17 | — | — | US | claimed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
| US-12637447-B2 | Carboxylic acid, acyl sulfonamide and acyl sulfamide-derivatized bicyclic aza-heteroaromatics as selective mcl-1 inhibitors and as dual mcl-1/bcl-2 inhibitors | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2026-05-26 | — | — | US | disclosed |
| CN-119977964-A | Chloro pyrrolo [4,3,2-de ] quinoline alkaloid and preparation method and application thereof | 河北工业大学 | 2025-05-13 | — | — | CN | disclosed |
| CN-119874711-A | Synthesis method and application of 1, 7-dichloroindolo [2,1-b ] quinazoline-6, 12-dione compound | 合肥工业大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119874711-A | Synthesis method and application of 1, 7-dichloroindolo [2,1-b ] quinazoline-6, 12-dione compound | 合肥工业大学 | 2025-04-25 | — | — | CN | disclosed |
| CN-119841836-A | 5H- [1,2,4] triazinyl [5,6-b ] indole derivatives containing disulfide structure, and preparation method and application thereof | 贵州大学 | 2025-04-18 | — | — | CN | disclosed |
| EP-0002624-A1 | 2-Benzazepine compounds, processes for their preparation and pharmaceutical compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4146718-A | BLOOD PLATELET ANTIAGGREGATIVE AGENT | BRISTOL-MYERS COMPANY (US) | 1979-03-27 | — | — | US | disclosed |
| US-4112096-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4112098-A | ANTIALLERGENS, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1978-09-05 | — | — | US | disclosed |
| US-4076818-A | ANTIALLERGENS | E. R. SQUIBB & SONS, INC. (US) | 1978-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070130702-A1 | Dyeing process using a specific compound containing active methylene and a compound chosen from a specific aldehyde, a specific ketone, a quinone and a diiminoisoindoline or 3-aminoisoindolone derivative | KRT18, NDUFB5, NDUFB7 | CES1 3158/4885TGM2 1920/4885NSD2 872/4885 |
| US-12637447-B2 | Carboxylic acid, acyl sulfonamide and acyl sulfamide-derivatized bicyclic aza-heteroaromatics as selective mcl-1 inhibitors and as dual mcl-1/bcl-2 inhibitors | MCL1, BCL2L1, BCL2L2 | CES1 1048/4885TGM2 4769/4885NSD2 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.