Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 3/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | IL1RN | P18510 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29792725 | 0.87 | F2 (0.57) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL35030 | 0.87 | F2 (0.57) | CA1CA2F2PRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL35219 | 0.85 | F2 (0.56) | CA1CA2F2PRSS1PRSS2 | |
| Methane SCHEMBL28888703 | 0.85 | F2 (0.56) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL1729812 | 0.81 | CA1 (0.51) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL2835612 | 0.79 | CA1 (0.71) | CA1CA2F2PRSS1PRSS2 | |
| Pyridine SCHEMBL9306571 | 0.78 | CYP2C19 (0.50) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL28004 | 0.77 | ALDH1A1 (0.58) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL29453108 | 0.77 | ALDH1A1 (0.58) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL27392366 | 0.75 | CYP2C19 (0.45) | CA1CA2F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104854110-B | Olanzapine haptens | 詹森药业有限公司 | 2016-12-28 | — | — | CN | disclosed |