Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | CA2 | P00918 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | F2 | P00734 | 3/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.65 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.65 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.59 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5991904 | 0.84 | CYP1A2 (0.53) | CA1CA2CYP1A2F2PRSS1 | |
| SCHEMBL15629008 | 0.84 | ALDH1A1 (0.63) | CA1CA2CYP1A2F2PRSS1 | |
| SCHEMBL3245644 | 0.84 | CA1 (0.68) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL22916896 | 0.84 | CA1 (0.68) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL3366244 | 0.82 | CA1 (0.66) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL35539 | 0.82 | CA1 (0.66) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL25517678 | 0.82 | CA1 (0.66) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL30147625 | 0.82 | CA1 (0.66) | CA1CA2F2PRSS1PRSS2 | |
| SCHEMBL10611041 | 0.81 | CYP1A2 (1.00) | CA1CA2CYP1A2F2PRSS1 | |
| SCHEMBL148204 | 0.80 | CA2 (0.54) | CA1CA2CYP1A2F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1320523-B1 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | claimed |
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | WARNER-LAMBERT COMPANY LLC | 2005-01-06 | — | — | US | claimed |
| EP-1320523-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | Warner-Lambert Company LLC (US) | 2003-06-25 | — | — | EP | claimed |
| US-6440896-B1 | FIRST DEVELOPER SOLUTION AND DISTINCT SECOND DEVELOPER SOLUTION PRODUCE DIFFERENT COLORS; COLOR STABILITY, WEAR RESISTANCE; INCORPORATING WITHIN A PROTECTIVE MEDIUM | EASTMAN KODAK COMPANY | 2002-08-27 | — | — | US | claimed |
| WO-2002024672-A2 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER-LAMBERT COMPANY LLC (US) | 2002-03-28 | — | — | WO | claimed |
| US-6197722-B1 | STORAGE STABILITY; IMAGES HAVING COLOR SATURATION AND COLOR GAMUT; INK JET PRINTING; NONSMEARING | EASTMAN KODAK COMPANY | 2001-03-06 | — | — | US | claimed |
| US-6143693-A | STORAGE STABILITY; ENABLES TO PRODUCE IMAGES HAVING COLOR SATURATION AND COLOR GAMUT, RESISTANCE TO DARK AND LIGHT FADE, RESISTANCE TO IMAGE SMEAR AND RUB-OFF, MOISTURE AND HUMIDITY RESISTANCE | EASTMAN KODAK COMPANY (US) | 2000-11-07 | — | — | US | claimed |
| US-5137916-A | Prevents, food spoilage, protein aging in animals | THE ROCKEFELLER UNIVERSITY (US) | 1992-08-11 | — | — | US | claimed |
| WO-1992002216-A2 | ADVANCED GLYCATION INHIBITORS CONTAINING AMINO-BENZOIC ACIDS AND DERIVATIVES, AND METHODS OF USE | THE ROCKEFELLER UNIVERSITY (US) | 1992-02-20 | — | — | WO | claimed |
| WO-1992002216-A1 | ADVANCED GLYCATION INHIBITORS CONTAINING AMINO-BENZOIC ACIDS AND DERIVATIVES, AND METHODS OF USE | UNIV ROCKEFELLER (US) | 1992-02-20 | — | — | WO | claimed |
| US-20100168101-A1 | OXINDOLE HYDRAZIDE MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2010-07-01 | — | — | US | disclosed |
| US-7696231-B2 | Oxindole hydrazide modulators of protein tyrosine phosphatases (PTPs) | LABORATOIRES SERONO SA (CH) | 2010-04-13 | — | — | US | disclosed |
| EP-1320523-B1 | BRANCHED CHAIN AMINO ACID-DEPENDENT AMINOTRANSFERASE INHIBITORS AND THEIR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES | WARNER LAMBERT CO (US) | 2005-06-22 | — | — | EP | disclosed |
| US-20050043388-A1 | Oxindole hydrazide modulators of protein tyrosine phosphatases (ptps) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. | 2005-02-24 | — | — | US | disclosed |
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | WARNER-LAMBERT COMPANY LLC | 2005-01-06 | — | — | US | disclosed |
| US-6197722-B1 | STORAGE STABILITY; IMAGES HAVING COLOR SATURATION AND COLOR GAMUT; INK JET PRINTING; NONSMEARING | EASTMAN KODAK COMPANY | 2001-03-06 | — | — | US | disclosed |
| US-6143693-A | STORAGE STABILITY; ENABLES TO PRODUCE IMAGES HAVING COLOR SATURATION AND COLOR GAMUT, RESISTANCE TO DARK AND LIGHT FADE, RESISTANCE TO IMAGE SMEAR AND RUB-OFF, MOISTURE AND HUMIDITY RESISTANCE | EASTMAN KODAK COMPANY (US) | 2000-11-07 | — | — | US | disclosed |
| US-5272176-A | Advanced glycation inhibitors containing amino-benzoic acids and derivatives, and methods of use | THE ROCKEFELLER UNIVERSITY (US) | 1993-12-21 | — | — | US | disclosed |
| US-5137916-A | Prevents, food spoilage, protein aging in animals | THE ROCKEFELLER UNIVERSITY (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992002216-A1 | ADVANCED GLYCATION INHIBITORS CONTAINING AMINO-BENZOIC ACIDS AND DERIVATIVES, AND METHODS OF USE | UNIV ROCKEFELLER (US) | 1992-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004167-A1 | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of neurodegenerative diseases | BCAT1, BCAT2, ABAT | CA1 2034/4885CA2 1859/4885CYP1A2 1698/4885 |
| US-20050043388-A1 | Oxindole hydrazide modulators of protein tyrosine phosphatases (ptps) | PTPRO, PTPRE, PTPRZ1 | CA1 3724/4885CA2 3098/4885CYP1A2 1603/4885 |
| US-20100168101-A1 | OXINDOLE HYDRAZIDE MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | PTPRO, PTPRE, PTPRZ1 | CA1 3729/4885CA2 3079/4885CYP1A2 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.