SCHEMBL35030

SCHEMBL35030

O=C(O)c1cccc(S(=O)(=O)Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.57
PRSS1 P07477 3/20 0.57
PRSS2 P07478 3/20 0.57
PRSS3 P35030 3/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
MAPT P10636 1/20 0.56
IL1RN P18510 1/20 0.56
CYP2C19 P33261 1/20 0.54
KDM4E B2RXH2 1/20 0.54
TSHR P16473 1/20 0.54
PTK2B Q14289 1/20 0.54
AKR1C3 P42330 5/20 0.53
ALDH1A1 P00352 2/20 0.53
AKR1C1 Q04828 1/20 0.53
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
MEP1B Q16820 1/20 0.51
CA12 O43570 1/20 0.50
CA6 P23280 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29792725 1.00 F2 (0.57) F2PRSS1PRSS2PRSS3CA1
Hydrochloric Acid SCHEMBL35219 0.98 F2 (0.56) F2PRSS1PRSS2PRSS3CA1
Methane SCHEMBL28888703 0.98 F2 (0.56) F2PRSS1PRSS2PRSS3CA1
SCHEMBL1729812 0.93 CA1 (0.51) F2PRSS1PRSS2PRSS3CA1
Pyridine SCHEMBL9306571 0.90 CYP2C19 (0.50) F2PRSS1PRSS2PRSS3CA1
SCHEMBL28122811 0.87 CA1 (0.54) F2PRSS1PRSS2PRSS3CA1
SCHEMBL6888383 0.86 LMNA (0.54) F2PRSS1PRSS2PRSS3CA1
SCHEMBL9822576 0.85 TDP1 (0.61) CA1CA2TSHRALDH1A1HSD17B10
SCHEMBL30525020 0.84 ALDH1A1 (0.46) F2PRSS1PRSS2PRSS3CA1
SCHEMBL35218 0.84 ALDH1A1 (0.46) F2PRSS1PRSS2PRSS3CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118666759-A Novel benzenesulfonamide compound and preparation method and application thereof 智元柏迈(杭州)科技有限公司 2024-09-20 CN claimed
EP-3946595-B1 CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR MODULATING AGENTS VERTEX PHARMA (US) 2023-11-15 EP claimed
CN-113117657-B Preparation and application of beta-cyclodextrin metal organic framework material HPLC column 中南民族大学 2022-12-13 CN claimed
CN-113801153-A Benzenesulfonyl amine HBV capsid protein inhibitor containing boric acid and boric acid pinacol ester group, and preparation method and application thereof 山东大学 2021-12-17 CN claimed
EP-0582247-B1 Method for the preparation of alkali metal salts of 3-sulphobenzoic acid HOECHST AG (DE) 1996-05-08 EP claimed
EP-0582248-B1 Method for the preparation of 3-sulphobenzoic acid and its alkali metal salts HOECHST AG (DE) 1996-03-13 EP claimed
US-5387711-A Mixing 3-(chlorosulfonyl)benzoic acid with water and a water-immiscible solvent in which the benzoic acid is insoluble; removing water; cooling HOECHST AG (DE) 1995-02-07 US claimed
US-5371281-A Heating 3-(chlorosulfonyl)benzoic acid with an aqueous alkali metal chloride solution; cooling; crystallization; separation HOECHST AG (DE) 1994-12-06 US claimed
EP-0212741-B1 A PROCESS FOR THE PREPARATION OF AN AZIDOSULPHONYLBENZOIC ACID SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-12-06 EP claimed
US-4666631-A Process for the preparation of an azidosulphonylbenzoic acid SHELL OIL COMPANY (US) 1987-05-19 US claimed
EP-0212741-A1 A process for the preparation of an azidosulphonylbenzoic acid SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-03-04 EP claimed
JP-6157453-A None JP disclosed
JP-6157452-A None JP disclosed
US-20260118751-A1 ORGANOMETALLIC COMPOUND, RESIST COMPOSITION COMPRISING THE SAME, AND PATTERN FORMATION METHOD USING THE RESIST COMPOSITION SAMSUNG ELECTRONICS CO., LTD. (KR) 2026-04-30 US disclosed
US-20260092058-A1 Small Molecule Degraders and Fluorescent Probes of PXR ST JUDE CHILDRENS RES HOSPITAL INC (US) 2026-04-02 US disclosed
US-4032344-A PHOTOSENSITIVITY EASTMAN KODAK COMPANY (US) 1977-06-28 US disclosed
US-4021245-A GELATION DERIVATIVE, SILICIC ACID ANHYDRIDE FUJI PHOTO FILM CO., LTD. (JA) 1977-05-03 US disclosed
US-3949079-A PLEUROMUTILIN; BACTERICIDES IN ANIMAL FEEDS BIOCHEMIE GES.M.B.H. (OE) 1976-04-06 US disclosed
US-3944502-A Process for preparing microcapsules containing hydrophobic oil drops FUJI PHOTO FILM CO., LTD. (JA) 1976-03-16 US disclosed
US-3943154-A PLANT AND ANIMAL GROWTH REGULATORS SANITIZED INCORPORATED (US) 1976-03-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260118751-A1 ORGANOMETALLIC COMPOUND, RESIST COMPOSITION COMPRISING THE SAME, AND PATTERN FORMATION METHOD USING THE RESIST COMPOSITION LBR, RER1, MNS1 F2 2392/4885PRSS1 4805/4885PRSS2 4778/4885
US-20260092058-A1 Small Molecule Degraders and Fluorescent Probes of PXR CRBN, VHL, NR1H4 F2 4322/4885PRSS1 2197/4885PRSS2 3776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.