Pyridine

Pyridine

SCHEMBL9306571

O=C(O)c1cccc(S(=O)(=O)Cl)c1.c1ccncc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.50
F2 P00734 3/20 0.49
PRSS1 P07477 3/20 0.49
PRSS2 P07478 3/20 0.49
PRSS3 P35030 3/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
MAPT P10636 1/20 0.48
IL1RN P18510 1/20 0.48
KMO O15229 1/20 0.47
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
KDM4E B2RXH2 1/20 0.47
TSHR P16473 1/20 0.47
PTK2B Q14289 1/20 0.47
AKR1C3 P42330 4/20 0.46
AKR1C1 Q04828 1/20 0.46
APP P05067 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29792725 0.90 F2 (0.57) CYP2C19F2PRSS1PRSS2PRSS3
SCHEMBL35030 0.90 F2 (0.57) CYP2C19F2PRSS1PRSS2PRSS3
Methane SCHEMBL28888703 0.88 F2 (0.56) CYP2C19F2PRSS1PRSS2PRSS3
Hydrochloric Acid SCHEMBL35219 0.88 F2 (0.56) CYP2C19F2PRSS1PRSS2PRSS3
SCHEMBL1729812 0.87 CA1 (0.51) CYP2C19F2PRSS1PRSS2PRSS3
SCHEMBL14572552 0.81 KMT2A (0.55) CA1CA2ALDH1A1HSD17B10TDP1
Isophthalic Acid SCHEMBL28446166 0.80 KMO (0.61) CA1CA2KMOALDH1A1HSD17B10
Pyridine SCHEMBL9404713 0.78 TDP1 (0.76) CA1CA2MAPTALDH1A1HSD17B10
SCHEMBL28122811 0.78 CA1 (0.54) CYP2C19F2PRSS1PRSS2PRSS3
SCHEMBL6888383 0.77 LMNA (0.54) F2PRSS1PRSS2PRSS3CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1036521-C Process for preparing ester of organic acid with alcohol derivatives of 19-nor steroids and their salts ROUSSEL UCLAF (FR) 1997-11-26 CN disclosed
US-5276023-A Antiglucocorticoids, progestational activity ROUSSEL UCLAF (FR) 1994-01-04 US disclosed
CN-1049352-A The alcohol derivate of using the 19-norsteroid prepares the method for new organic acid acetic and salt thereof ROUSSEL UCLAF (FR) 1991-02-20 CN disclosed