Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 4/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810473 | 0.78 | TRPV4 (0.41) | TRPV4 | |
| SCHEMBL16555923 | 0.77 | TRPV4 (0.69) | TRPV4ESR1ESR2 | |
| SCHEMBL718612 | 0.76 | CA3 (0.42) | EGFRFBP1ESR1ESR2 | |
| SCHEMBL1544963 | 0.74 | PTGDR2 (0.36) | EGFRFBP1 | |
| SCHEMBL17787791 | 0.73 | EGFR (0.32) | EGFRFBP1ESR1ESR2 | |
| SCHEMBL27280801 | 0.73 | TRPV4 (0.47) | TRPV4 | |
| SCHEMBL2809900 | 0.73 | ESR1 (0.45) | ESR1ESR2 | |
| SCHEMBL5958536 | 0.73 | PYCR1 (0.39) | EGFRFBP1ESR1ESR2 | |
| SCHEMBL2897973 | 0.73 | NFE2L2 (0.36) | EGFRFBP1ESR1ESR2 | |
| SCHEMBL641650 | 0.73 | EGFR (0.35) | EGFRFBP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | FUJIFILM CORPORATION (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2202221-A1 | ACETYLENE COMPOUND | Fujifilm Corporation (JP) | 2010-06-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240908-A1 | ACETYLENE COMPOUND | NAT1, KATNA1, KAT2B | TRPV4 2447/4885EGFR 3100/4885FBP1 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.