Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28124773 | 0.83 | TDP1 (0.55) | ALDH1A1HTTTDP1L3MBTL1NPSR1 | |
| SCHEMBL17335022 | 0.81 | TDP1 (0.42) | ALDH1A1HTTTDP1L3MBTL1NPSR1 | |
| SCHEMBL283180 | 0.79 | SMN1; SMN2 (0.47) | ALDH1A1HTTTDP1L3MBTL1NPSR1 | |
| SCHEMBL27415134 | 0.79 | PDK1 (0.41) | ALDH1A1NPSR1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL28124769 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HTTTDP1L3MBTL1NPSR1 | |
| SCHEMBL27448923 | 0.79 | KMT2A (0.40) | ALDH1A1HTTNPSR1KMT2ALMNA | |
| SCHEMBL28124280 | 0.78 | TDP1 (0.37) | ALDH1A1HTTTDP1L3MBTL1NPSR1 | |
| SCHEMBL1143703 | 0.77 | ALDH1A1 (0.48) | ALDH1A1TDP1L3MBTL1KMT2ALMNA | |
| SCHEMBL27570720 | 0.76 | ALDH1A1 (0.46) | ALDH1A1HTTNPSR1KMT2ASMN1; SMN2 | |
| SCHEMBL27720989 | 0.75 | GPR35 (0.46) | ALDH1A1HTTTDP1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459012-A | Quinazolinone derivatives as phosphatidylinositol 3-kinase inhibitors | 吉利德科学公司 | 2017-02-22 | — | — | CN | disclosed |