Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448923 | 0.91 | KMT2A (0.40) | VCAM1ALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL27337266 | 0.82 | PDK1 (0.37) | PDK1VCAM1ALDH1A1HPGDNPSR1 | |
| SCHEMBL27332233 | 0.82 | VCAM1 (0.38) | PDK1VCAM1ALDH1A1HPGDNPSR1 | |
| SCHEMBL27832784 | 0.81 | VCAM1 (0.55) | VCAM1ALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL28791798 | 0.81 | ITGB1 (0.51) | VCAM1ALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL6953347 | 0.81 | PDK1 (0.46) | PDK1VCAM1ALDH1A1HPGDNPSR1 | |
| SCHEMBL27416551 | 0.80 | TSHR (0.55) | VCAM1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL1018568 | 0.79 | VCAM1 (0.58) | PDK1VCAM1ALDH1A1HPGDNPSR1 | |
| SCHEMBL28824451 | 0.79 | ATM (0.42) | VCAM1ALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL28124282 | 0.79 | ALDH1A1 (0.40) | ALDH1A1NPSR1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117569-C | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORP (US) | 2003-08-13 | — | — | CN | disclosed |
| CN-1143323-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORP (US) | 1997-02-19 | — | — | CN | disclosed |