Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 9/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28740575 | 0.83 | CYP1A2 (0.41) | KDM4EPDPK1GAACYP3A4CYP1A2 | |
| SCHEMBL29481432 | 0.79 | PDPK1 (1.00) | KDM4EPDPK1GAACYP3A4CYP1A2 | |
| SCHEMBL18878 | 0.79 | PDPK1 (1.00) | KDM4EPDPK1GAACYP3A4CYP1A2 | |
| Urea SCHEMBL2190330 | 0.74 | KDM4E (0.80) | KDM4EPDPK1GAACYP3A4CYP1A2 | |
| Bicarbonate SCHEMBL1573525 | 0.74 | KDM4E (0.80) | KDM4EPDPK1GAACYP3A4CYP1A2 | |
| Carbamic Acid SCHEMBL1857015 | 0.73 | KDM4E (0.77) | KDM4EPDPK1GAACYP3A4CYP1A2 | |
| Trifluoroacetic Acid SCHEMBL18096685 | 0.71 | KDM4E (0.67) | KDM4EPDPK1GAACYP3A4STAT3 | |
| SCHEMBL9042255 | 0.71 | KDM4E (0.73) | KDM4EPDPK1GAACYP3A4CYP1A2 | |
| Methylethylamine SCHEMBL15526348 | 0.69 | PDPK1 (0.69) | KDM4EPDPK1GAACYP3A4CYP1A2 | |
| SCHEMBL21965345 | 0.68 | RARG (0.50) | KDM4EPDPK1GAACYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106414440-A | Aryl and heteroaryl substituted imidazo [1,2-a ] pyridine-3-carboxamides and their use | 拜耳制药股份公司 | 2017-02-15 | — | — | CN | disclosed |