SCHEMBL28124653

SCHEMBL28124653

FC(F)(F)c1ccc2c(c1)sc1ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.54
ALDH1A1 P00352 3/20 0.53
MAPT P10636 2/20 0.53
HPGD P15428 1/20 0.53
RAB9A P51151 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
KIF11 P52732 4/20 0.49
EPHX2 P34913 2/20 0.42
SCN4A P35499 1/20 0.42
MPI P34949 2/20 0.42
PHOSPHO1 Q8TCT1 2/20 0.42
PMM2 O15305 1/20 0.42
G6PD P11413 1/20 0.40
TLR9 Q9NR96 1/20 0.40
POLB P06746 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.38
F10 P00742 1/20 0.38
CYBB P04839 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14617357 0.81 GPR3 (0.54) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL11635447 0.80 KIF11 (0.49) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL30369262 0.79 KDM4E (0.58) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL26820448 0.79 KIF11 (0.50) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL26820467 0.79 KIF11 (0.50) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL2810528 0.79 KDM4E (0.58) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL24617994 0.78 ALDH1A1 (0.50) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL14173395 0.78 ALDH1A1 (0.50) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL4586334 0.78 KIF11 (0.51) KIF11EPHX2SCN4A
SCHEMBL29196036 0.78 EPHX2 (0.37) ALDH1A1MAPTHPGDRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106397397-B Diaryl and episulfide and selenides and its synthesis and application 华东师范大学 2019-02-01 CN claimed
CN-106397397-A Diaryl ring fused sulfides and diaryl ring fused selenides, and synthesis method and application thereof 华东师范大学 2017-02-15 CN claimed
CN-112552279-B Synthesis method of substituted dibenzothiophene compound 郑州海阔光电材料有限公司 2023-02-24 CN disclosed
CN-112552279-A Synthesis method of substituted dibenzothiophene compound 郑州海阔光电材料有限公司 2021-03-26 CN disclosed
CN-109554181-A Liquid crystal media and liquid crystal display comprising it 默克专利股份有限公司 2019-04-02 CN disclosed
CN-106397397-B Diaryl and episulfide and selenides and its synthesis and application 华东师范大学 2019-02-01 CN disclosed
CN-106397397-A Diaryl ring fused sulfides and diaryl ring fused selenides, and synthesis method and application thereof 华东师范大学 2017-02-15 CN disclosed