Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | EPM2A | O95278 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | MPI | P34949 | 2/20 | 0.39 |
| ▸ | PHOSPHO1 | Q8TCT1 | 2/20 | 0.39 |
| ▸ | PMM2 | O15305 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2810528 | 0.81 | KDM4E (0.58) | KIF11GPR3G6PDTLR9EPM2A | |
| SCHEMBL30369262 | 0.81 | KDM4E (0.58) | KIF11GPR3G6PDTLR9EPM2A | |
| SCHEMBL28124653 | 0.80 | GPR3 (0.54) | KIF11GPR3G6PDTLR9EPHX2 | |
| SCHEMBL9129456 | 0.79 | GPR3 (0.68) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| Hydrochloric Acid SCHEMBL29008118 | 0.77 | GPR3 (0.65) | GPR3ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL28344832 | 0.75 | GPR3 (0.46) | GPR3PTPN22MPIPHOSPHO1PMM2 | |
| SCHEMBL1285223 | 0.75 | KDM4E (0.64) | GPR3G6PDALDH1A1MAPTHPGD | |
| SCHEMBL26820448 | 0.75 | KIF11 (0.50) | KIF11GPR3EPHX2EPM2APTPN2 | |
| SCHEMBL26820467 | 0.75 | KIF11 (0.50) | KIF11GPR3EPHX2EPM2APTPN2 | |
| SCHEMBL16421246 | 0.74 | G6PD (0.47) | KIF11G6PDTLR9EPHX2EPM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4089961-A | Antipsychotically useful quinolizidylidene derivatives of xanthenes, thioxanthenes and dibenzoxepins | SMITHKLINE CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |