SCHEMBL2812609

SCHEMBL2812609

Cc1c(O)c(C)c(CCl)c(C)c1CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL258408 0.84
Methoxymethane SCHEMBL7618244 0.79 IGF1R (0.33)
SCHEMBL10495933 0.78 SIRT1 (0.32)
SCHEMBL2813869 0.78
SCHEMBL30671673 0.78
SCHEMBL4445015 0.77
SCHEMBL30539353 0.77
SCHEMBL10495951 0.76 ALDH1A1 (0.37)
SCHEMBL8924397 0.74 IMPDH2 (0.40)
SCHEMBL11522240 0.74 TSHR (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117209534-A Phosphine ligand compound with phenol group and preparation method and application thereof 中国石油化工股份有限公司 2023-12-12 CN claimed
CN-117209534-A Phosphine ligand compound with phenol group and preparation method and application thereof 中国石油化工股份有限公司 2023-12-12 CN disclosed
CN-117209364-A Substituted phenol compound and preparation method and application thereof 中国石油化工股份有限公司 2023-12-12 CN disclosed
US-20100240713-A1 AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS XENON PHARMACEUTICALS INC. (CA) 2010-09-23 US disclosed
EP-2068855-A2 AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS XENON PHARMACEUTICALS INC. (CA) 2009-06-17 EP disclosed
WO-2008151288-A2 AROMATIC AND HETEROAROMATIC COMPOUNDS USEFUL IN TREATING IRON DISORDERS XENON PHARMACEUTICALS INC. (CA) 2008-12-11 WO disclosed
EP-0252006-B1 SUBSTITUTED PHENOLS AND THEIR USE AS STABILIZING AGENTS CIBA-GEIGY AG (CH) 1990-02-28 EP disclosed
US-4820756-A Thioether substituted phenols and their use as stabilizers CIBA-GEIGY CORPORATION (US) 1989-04-11 US disclosed
EP-0252006-A1 Substituted phenols and their use as stabilizing agents CIBA-GEIGY AG (CH) 1988-01-07 EP disclosed
US-4225450-A Lubricant compositions containing dithiocarbamyl antioxidants CIBA-GEIGY CORPORATION (US) 1980-09-30 US disclosed
EP-0000514-A1 Phenol-N,N-dioctyl esters of dithiocarbamic acid and lubricants stabilized therewith CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed