Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 2/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6270232 | 0.77 | CDK1 (0.53) | PDE8B | |
| SCHEMBL3089517 | 0.75 | CDK1 (0.54) | PDE8B | |
| SCHEMBL12283253 | 0.69 | CDK1 (0.35) | — | |
| SCHEMBL12261690 | 0.69 | CDK1 (0.35) | — | |
| SCHEMBL11555756 | 0.67 | LMNA (0.42) | — | |
| SCHEMBL3245638 | 0.67 | PDPK1 (0.53) | — | |
| SCHEMBL12344427 | 0.65 | CDK1 (0.36) | — | |
| SCHEMBL17800816 | 0.65 | PDPK1 (0.54) | — | |
| SCHEMBL1693586 | 0.64 | TDO2 (0.38) | PDE8BPDE10AHRH4 | |
| SCHEMBL28147887 | 0.64 | PDE10A (0.55) | PDE8BPDE10AGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106456580-A | Heterocyclic hydroxamic acids as protein deacetylase inhibitors and dual protein deacetylase-protein kinase inhibitors and methods of use thereof | 科罗拉多州立大学董事会法人团体 | 2017-02-22 | — | — | CN | disclosed |