SCHEMBL28126253

SCHEMBL28126253

CC1c2ccccc2NC1(C)C

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTR5A P47898 10/20 0.39
CREBBP Q92793 2/20 0.35
BRPF1 P55201 1/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 1/20 0.34
RAD52 P43351 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
BRD4 O60885 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2257038 0.79 PGR (0.38) HTR5ACREBBPBRPF1ALDH1A1CYP3A4
SCHEMBL31267142 0.79 PGR (0.38) HTR5ACREBBPBRPF1ALDH1A1CYP3A4
SCHEMBL28616194 0.79 HTR5A (0.37) HTR5ACREBBPBRPF1ALDH1A1CYP3A4
SCHEMBL13431346 0.78 PGR (0.38) HTR5A
SCHEMBL9156505 0.77 PGR (0.36) HTR5AALDH1A1CYP3A4HSD17B10TDP1
SCHEMBL11137818 0.74 KDM4E (0.41) ALDH1A1MAPTRAD52KDM4EMEN1
SCHEMBL1161239 0.74 KDM4E (0.37) HTR5AALDH1A1CYP3A4HSD17B10TDP1
SCHEMBL8010752 0.72 ALDH1A1 (0.46) CREBBPBRPF1ALDH1A1CYP3A4HSD17B10
SCHEMBL22798311 0.72 ALDH1A1 (0.33) HTR5ACREBBPBRPF1ALDH1A1CYP3A4
SCHEMBL1161494 0.72 EGFR (0.33) HTR5ACREBBPBRPF1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106511337-B Application of heptamethine indole cyanine dyes 中国人民解放军第三军医大学 2020-08-21 CN disclosed
CN-106511337-A Application of heptamethine indole cyanine dyes 中国人民解放军第三军医大学 2017-03-22 CN disclosed