Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | HTR5A | P47898 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13431346 | 0.80 | PGR (0.38) | PGRHTR5A | |
| SCHEMBL28126253 | 0.77 | HTR5A (0.39) | HTR5AALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL27870432 | 0.75 | HTR5A (0.38) | HTR5AALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL1095905 | 0.73 | HSD17B10 (0.40) | PGRALDH1A1HSD17B10KDM4EMEN1 | |
| SCHEMBL3836466 | 0.73 | ALDH1A1 (0.42) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1161239 | 0.72 | KDM4E (0.37) | HTR5AALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL30099098 | 0.72 | EGFR (0.38) | HTR5AALDH1A1HSD17B10KDM4ESMN1; SMN2 | |
| SCHEMBL1119046 | 0.72 | ALDH1A1 (0.39) | HTR5AALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL22798311 | 0.71 | ALDH1A1 (0.33) | HTR5AALDH1A1CYP3A4HSD17B10TDP1 | |
| SCHEMBL842873 | 0.71 | PDK2 (0.44) | HTR5AALDH1A1TDP1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451607-A | APPLYING HYDRAZONE DERIVATIVE TO A LOCUS TO CONTROL PESTS | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-09-19 | — | — | US | disclosed |
| CN-1078460-A | The method for making of hydrazone derivative and application | SUMITOMO CHEMICAL CO (JP) | 1993-11-17 | — | — | CN | disclosed |
| EP-0567138-A2 | Hydrazone derivatives, process for producing the same, insecticides and/or acaricides containing the same as active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-10-27 | — | — | EP | disclosed |