Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 3/20 | 0.48 |
| ▸ | BCR | P11274 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352615 | 0.83 | KDM4E (0.53) | ABL1BCRCA12CA1CA2 | |
| SCHEMBL5324303 | 0.79 | RARA (0.52) | ABL1BCRCA12CA1CA2 | |
| SCHEMBL8117503 | 0.79 | CYP17A1 (0.57) | GPR119HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15090620 | 0.78 | LTA4H (0.47) | GPR119ABL1BCRPDPK1ADRB2 | |
| SCHEMBL15194111 | 0.78 | ABL1 (0.55) | GPR119ABL1BCRHDAC3HDAC4 | |
| SCHEMBL21777058 | 0.77 | ABL1 (0.57) | GPR119ABL1BCRHDAC3HDAC4 | |
| SCHEMBL8220821 | 0.77 | ADRB2 (0.56) | GPR119HDAC1HDAC6ADRB2LOXL2 | |
| SCHEMBL533580 | 0.77 | GPR119 (0.47) | GPR119ABL1BCRPDPK1ADRB2 | |
| SCHEMBL6350965 | 0.77 | CA12 (0.71) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2177044 | 0.76 | PDPK1 (0.60) | ABL1BCRHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106674148-A | Preparation method of (5-halogenothiazole-2-yl) benzoic acid compounds | 苏州汉德创宏生化科技有限公司 | 2017-05-17 | — | — | CN | disclosed |