SCHEMBL28128148

SCHEMBL28128148

C1=Cc2ccccc2C(c2ccccc2)(c2ccccc2)C1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.32
AKR1C1 Q04828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30897428 0.79 GAA (0.32)
SCHEMBL4885179 0.77 PNMT (0.34)
SCHEMBL2164738 0.73 HDAC4 (0.31) HDAC4
SCHEMBL9657283 0.73 MEN1 (0.33)
SCHEMBL7873676 0.73
SCHEMBL3209428 0.73 HDAC4 (0.31) HDAC4AKR1C1
SCHEMBL11237119 0.71 HDAC4 (0.33) HDAC4
SCHEMBL8992358 0.71 CYP2C9 (0.38) HDAC4AKR1C1
SCHEMBL31650443 0.71 SIGMAR1 (0.31)
SCHEMBL4369386 0.71 HIF1A (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106478567-B A kind of method preparing chiral 2- methylene -2,3- dihydro-naphtho [2,1-b] furfuran compound 中国科学院大连化学物理研究所 2019-02-15 CN disclosed
CN-106478567-A One kind prepares chiral 2- methylene -2, the method for 3- dihydro-naphtho [2,1-b] furfuran compound 中国科学院大连化学物理研究所 2017-03-08 CN disclosed