Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992349 | 0.79 | MAOB (0.34) | OPRM1OPRL1OPRK1MAPTKCNH2 | |
| SCHEMBL11237119 | 0.74 | HDAC4 (0.33) | HDAC4OPRM1OPRL1OPRK1 | |
| SCHEMBL2153575 | 0.72 | KMT2A (0.36) | CYP2C9MEN1KMT2AALDH1A1AKR1C1 | |
| SCHEMBL15657386 | 0.69 | CFTR (0.45) | CYP2C9MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL6603582 | 0.65 | ALDH1A1 (0.38) | CYP2C9MEN1KMT2AHDAC4ALDH1A1 | |
| SCHEMBL29369468 | 0.65 | MAPT (0.32) | ALDH1A1MAPTPOLBTSHRTDP1 | |
| SCHEMBL576510 | 0.64 | KMT2A (0.40) | CYP2C9MEN1KMT2AALDH1A1AKR1C1 | |
| SCHEMBL11489569 | 0.64 | MEN1 (0.50) | CYP2C9MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL29883511 | 0.62 | MEN1 (0.48) | CYP2C9MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL28634495 | 0.61 | OPRM1 (0.32) | CYP2C9MEN1KMT2AHDAC4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445749-B1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5256824-A | Anticholinergic agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-10-26 | — | — | US | disclosed |
| EP-0445749-A1 | N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |