Diphenylether

Diphenylether

SCHEMBL28129014

CCCCC(=O)O.OCCO.c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 5/20 0.53
FFAR1 O14842 4/20 0.53
POLB P06746 1/20 0.52
ATM Q13315 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
HDAC3 O15379 1/20 0.49
FFAR4 Q5NUL3 4/20 0.48
SRD5A2 P31213 1/20 0.46
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
MAPT P10636 2/20 0.46
ALDH1A1 P00352 1/20 0.46
GAA P10253 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
AKR1B1 P15121 1/20 0.45
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Myristic Acid SCHEMBL29013228 0.88 GPR84 (0.61) LTA4HFFAR1FFAR4CES2CES1
Diphenylether SCHEMBL6560478 0.83 FFAR1 (0.52) LTA4HFFAR1SRD5A2ALDH1A1
Diphenylether SCHEMBL30565429 0.83 FFAR1 (0.66) LTA4HFFAR1HDAC3FFAR4SRD5A2
Anisole SCHEMBL30807530 0.82 PDE4B (0.57) FFAR1POLBATML3MBTL1FFAR4
Anisole SCHEMBL9776748 0.82 PDE4B (0.57) FFAR1POLBATML3MBTL1FFAR4
Diphenylether SCHEMBL8103449 0.81 LTA4H (0.64) LTA4HPOLBATML3MBTL1HDAC3
Diphenylether SCHEMBL896890 0.79 LTA4H (0.55) LTA4HFFAR1SRD5A2MAPTALDH1A1
Diphenylether SCHEMBL5918274 0.79 FFAR1 (0.70) LTA4HFFAR1FFAR4SRD5A2
Diphenylether SCHEMBL1756150 0.79 LTA4H (0.60) LTA4HHDAC3MAPTALDH1A1GAA
Valeric Acid SCHEMBL27773247 0.79 AKR1B1 (0.70) FFAR1HDAC3FFAR4MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106458831-A Method for manufacturing low VOC coalescing aids 陶氏环球技术有限责任公司 2017-02-22 CN disclosed