Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28129462 | 0.87 | F2 (0.47) | KDM5BKDM4AKDM5AKDM4CF2 | |
| SCHEMBL30105384 | 0.81 | LOXL2 (0.60) | F2IDO1PCSK9OPRK1LOXL2 | |
| SCHEMBL3193871 | 0.81 | LOXL2 (0.60) | F2IDO1PCSK9OPRK1LOXL2 | |
| SCHEMBL27628586 | 0.80 | CTSV (0.50) | MTNR1AMTNR1BKDM4EMAPTDAO | |
| Bromide SCHEMBL30437340 | 0.80 | LOXL2 (0.58) | F2IDO1PCSK9OPRK1LOXL2 | |
| Hydrochloric Acid SCHEMBL27754931 | 0.80 | LOXL2 (0.58) | F2IDO1OPRK1LOXL2 | |
| SCHEMBL7648523 | 0.79 | KDM5B (0.60) | KDM5BKDM4AKDM5AKDM4CF2 | |
| SCHEMBL6989629 | 0.76 | PCSK9 (0.55) | F2DAOPCSK9OPRK1LOXL2 | |
| Acetic Acid SCHEMBL9551967 | 0.76 | MTNR1A (0.50) | F2MTNR1AMTNR1BIDO1KDM4E | |
| SCHEMBL27372960 | 0.75 | KDM4E (0.43) | IDO1KDM4EMAPTDAOHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104804004-B | A kind of preparation method of chiral hexahydropyrrolo diindyl class compound | 安徽师范大学 | 2017-03-29 | — | — | CN | disclosed |