Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28130384 | 0.85 | KDM4E (0.68) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28602079 | 0.80 | PLA2G2A (0.58) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL16832843 | 0.79 | PLA2G2A (0.69) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28100426 | 0.79 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28100530 | 0.78 | ALDH1A1 (0.64) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28100420 | 0.78 | PLA2G2A (0.58) | KDM4EHSD17B10ALDH1A1HPGDPLA2G2A | |
| SCHEMBL28608277 | 0.77 | CFTR (0.51) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28100421 | 0.76 | NQO2 (0.44) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL15129579 | 0.76 | KDM4E (0.73) | KDM4EHSD17B10ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28100588 | 0.76 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106029647-A | Glucose transport inhibitors | 拜耳制药股份公司 | 2016-10-12 | — | — | CN | disclosed |