Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.55 |
| ▸ | KMO | O15229 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917353 | 0.93 | CYP17A1 (0.57) | MAPKAPK2KMOKDM4EMEN1MAPT | |
| SCHEMBL25118560 | 0.90 | IDO1 (0.55) | MAPKAPK2KMOKDM4EMEN1MAPT | |
| SCHEMBL4854402 | 0.83 | GABRG2 (0.60) | MAPKAPK2KMOPIM1GABRG2GABRB3 | |
| SCHEMBL842168 | 0.83 | CYP2A6 (0.57) | MAPKAPK2KMOKDM4EMEN1MAPT | |
| SCHEMBL4227 | 0.83 | KMO (0.49) | MAPKAPK2KMOKDM4EMEN1MAPT | |
| SCHEMBL25492416 | 0.83 | KMO (0.49) | MAPKAPK2KMOKDM4EMEN1MAPT | |
| SCHEMBL27735978 | 0.82 | MAP4K4 (0.53) | MAPKAPK2KMOKDM4EMEN1MAPT | |
| SCHEMBL14979564 | 0.81 | ASIC3 (0.47) | MAPKAPK2KMOGRM5IDO1TAAR1 | |
| SCHEMBL29398603 | 0.81 | GRM5 (0.59) | KMOKDM4EMEN1MAPTKMT2A | |
| SCHEMBL2480128 | 0.81 | GRM5 (0.59) | KMOKDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822663-B | Substituted N (3 (4 base of pyrimidine) phenyl) acrylamide as tyrosine receptor kinase BTK inhibitor is similar to thing | 犹他大学研究基金会 | 2017-03-08 | — | — | CN | disclosed |