SCHEMBL2480128

SCHEMBL2480128

Fc1cccc(-c2cccc(-c3ccccn3)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 3/20 0.59
DCTPP1 Q9H773 1/20 0.50
BCHE P06276 1/20 0.50
ACHE P22303 1/20 0.50
TLR4 O00206 1/20 0.48
TLR2 O60603 1/20 0.48
CYP2A6 P11509 1/20 0.47
KDM4E B2RXH2 3/20 0.46
LMNA P02545 2/20 0.46
CCR1 P32246 2/20 0.46
CCR5 P51681 2/20 0.46
CCR8 P51685 2/20 0.46
CYP1A2 P05177 1/20 0.46
POLB P06746 1/20 0.46
METAP1 P53582 1/20 0.46
BLM P54132 1/20 0.46
HIF1A Q16665 1/20 0.46
DOHH Q9BU89 1/20 0.46
P4HTM Q9NXG6 1/20 0.46
HPGDS O60760 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29398603 1.00 GRM5 (0.59) GRM5DCTPP1BCHEACHETLR4
SCHEMBL3767444 0.98 GRM5 (0.57) GRM5DCTPP1BCHEACHETLR4
SCHEMBL29883580 0.96 GRM5 (0.62) GRM5DCTPP1BCHEACHETLR4
SCHEMBL3233604 0.96 GRM5 (0.62) GRM5DCTPP1BCHEACHETLR4
SCHEMBL4026544 0.94 GRM5 (0.60) GRM5DCTPP1BCHEACHETLR4
SCHEMBL21506994 0.88 KDM4E (0.59) GRM5TLR4TLR2CYP2A6KDM4E
SCHEMBL29395137 0.87 TGFBR1 (0.49) GRM5TLR4TLR2CYP2A6KDM4E
SCHEMBL17306553 0.87 TGFBR1 (0.49) GRM5TLR4TLR2CYP2A6KDM4E
SCHEMBL21173056 0.86 KDM4E (0.56) GRM5TLR4TLR2CYP2A6KDM4E
SCHEMBL11910168 0.86 KDM4E (0.56) GRM5TLR4TLR2CYP2A6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114106058-A Preparation method and application of aggregation-induced emission platinum complex 大连理工大学 2022-03-01 CN claimed
CN-114106058-B Preparation method and application of aggregation-induced emission platinum complex 大连理工大学 2023-09-12 CN disclosed
CN-114106058-A Preparation method and application of aggregation-induced emission platinum complex 大连理工大学 2022-03-01 CN disclosed
EP-3855519-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2021-07-28 EP disclosed
EP-3428986-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2021-01-20 EP disclosed
EP-3428986-A1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2019-01-16 EP disclosed
EP-1763902-B1 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2018-08-29 EP disclosed
US-8603645-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2013-12-10 US disclosed
US-8449990-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2013-05-28 US disclosed
EP-2378582-A1 Stable and efficient electroluminescent materials Universal Display Corporation (US) 2011-10-19 EP disclosed
US-20110060143-A1 Stable and Efficient Electroluminescent Materials KWONG RAYMOND 2011-03-10 US disclosed
US-7851072-B2 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORATION (US) 2010-12-14 US disclosed
US-20100176390-A1 ELECTROLUMINESCENT EFFICIENCY KWONG RAYMOND 2010-07-15 US disclosed
US-7709100-B2 Electroluminescent efficiency UNIVERSAL DISPLAY CORPORATION (US) 2010-05-04 US disclosed
EP-1763902-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS Universal Display Corporation (US) 2007-03-21 EP disclosed
US-20070003789-A1 Stable and efficient electroluminescent materials UNIVERSAL DISPLAY CORPORAITON 2007-01-04 US disclosed
WO-2006014599-A2 STABLE AND EFFICIENT ELECTROLUMINESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2006-02-09 WO disclosed
US-20060008673-A1 Electroluminescent efficiency THE UNIVERSITY OF SOUTHERN CALIFORNIA 2006-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060008673-A1 Electroluminescent efficiency EML4, LEF1, ESR1 GRM5 609/4885DCTPP1 3746/4885BCHE 2152/4885
US-20100176390-A1 ELECTROLUMINESCENT EFFICIENCY EML4, LEF1, ESR1 GRM5 1043/4885DCTPP1 3645/4885BCHE 2259/4885
US-20110060143-A1 Stable and Efficient Electroluminescent Materials EML4, ITGA5, CHRM5 GRM5 38/4885DCTPP1 4037/4885BCHE 2501/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.