Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 10/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2816860 | 0.91 | ADORA2B (0.43) | ADORA2BADORA3ADORA2AADORA1MEN1 | |
| SCHEMBL2815140 | 0.88 | CA12 (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL2816988 | 0.85 | ADORA2A (0.45) | ADORA2BADORA3ADORA2AADORA1CA12 | |
| SCHEMBL2816527 | 0.85 | CA12 (0.42) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL2815672 | 0.84 | RAB9A (0.45) | ADORA2BADORA3ADORA2AADORA1CA12 | |
| SCHEMBL2819439 | 0.83 | IDH1 (0.49) | ADORA2BADORA3ADORA2AADORA1MEN1 | |
| SCHEMBL2812011 | 0.80 | MEN1 (0.45) | ADORA2BADORA3ADORA2AADORA1MEN1 | |
| SCHEMBL3998145 | 0.78 | CA12 (0.45) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL2815561 | 0.78 | MAPT (0.44) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3991433 | 0.78 | MEN1 (0.42) | ADORA2BADORA2AADORA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249132-A1 | IMIDAZOLE DERIVATIVES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-09-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249132-A1 | IMIDAZOLE DERIVATIVES | SDHA, SDHB, TPD52L2 | ADORA2B 2363/4885ADORA3 3048/4885ADORA2A 3363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.