Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL27723867 | 0.89 | CA2 (0.73) | CA2CA4CA5AESR1SRC | |
| Methyl Phosphonate SCHEMBL28145526 | 0.89 | — | — | |
| Toluene SCHEMBL28836845 | 0.82 | LMNA (0.52) | CA2CA4CA5AESR1SRC | |
| Methyl Phosphonate SCHEMBL29461628 | 0.76 | CA2 (1.00) | CA2 | |
| Methyl Phosphonate SCHEMBL21791 | 0.76 | — | — | |
| Methyl Phosphonate SCHEMBL21462989 | 0.72 | — | — | |
| Pyridine SCHEMBL10628255 | 0.71 | TSHR (0.53) | CA2CA4CA5A | |
| Biphenyl SCHEMBL377328 | 0.71 | ACP3 (0.54) | CA2CA4CA5AESR1SRC | |
| Benzene SCHEMBL341618 | 0.71 | CA2 (0.47) | CA2CA4CA5ASRCCFTR | |
| Methyl Phosphonate SCHEMBL2403918 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646585-B | A kind of preparation method of (R) 9 [2 (phosphonium mesitoyl methoxy) propyl group] adenine | 扬州三友合成化工有限公司 | 2018-03-13 | — | — | CN | claimed |
| CN-107602613-A | A kind of preparation method of (R) 9 [2 (phosphonium mesitoyl methoxy) propyl group] adenine | 常州润联化工有限公司 | 2018-01-19 | — | — | CN | claimed |
| CN-106699814-A | Preparation method of adefovir dipivoxil crystals | 辰欣药业股份有限公司 | 2017-05-24 | — | — | CN | claimed |
| CN-109053799-A | A kind of synthetic method of tolysulfonyl oxygen methylphosphonic acid diethylester | 乐平市赛复乐医药化工有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109053804-A | A kind of synthetic method of tenofovir | 乐平市赛复乐医药化工有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-109021011-A | A method of synthesis tolysulfonyl oxygen methylphosphonic acid diethylester | 山东沾化永浩医药科技有限公司 | 2018-12-18 | — | — | CN | disclosed |
| CN-108627647-A | A kind of detection of posttranslational modification proteomics and quantitative approach | 四川大学 | 2018-10-09 | — | — | CN | disclosed |
| CN-108358968-A | A kind of preparation method of high-purity tenofovir | 山东科兴生物制品有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105646585-B | A kind of preparation method of (R) 9 [2 (phosphonium mesitoyl methoxy) propyl group] adenine | 扬州三友合成化工有限公司 | 2018-03-13 | — | — | CN | disclosed |
| CN-106699814-A | Preparation method of adefovir dipivoxil crystals | 辰欣药业股份有限公司 | 2017-05-24 | — | — | CN | disclosed |
| CN-103848868-B | method for preparing tenofovir | 蚌埠丰原涂山制药有限公司 | 2017-04-12 | — | — | CN | disclosed |
| CN-106432330-A | Intermediate compound of medicine LB80380 and preparing method and application thereof | 天津科伦药物研究有限公司 | 2017-02-22 | — | — | CN | disclosed |