Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.58 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.47 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.47 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL13279853 | 0.90 | LMNA (0.52) | ALDH1A1TRIM24TRIM33LMNAMAPK1 | |
| Glutarate SCHEMBL28228789 | 0.90 | TRIM24 (0.52) | ALDH1A1TRIM24TRIM33LMNAMAPK1 | |
| SCHEMBL3271667 | 0.88 | TSHR (0.55) | ALDH1A1TRIM24TRIM33LMNAHSD17B10 | |
| Adipic Acid SCHEMBL28157377 | 0.87 | LMNA (0.55) | ALDH1A1TRIM24TRIM33LMNASLC22A6 | |
| Adipic Acid SCHEMBL28266136 | 0.87 | LMNA (0.55) | ALDH1A1TRIM24TRIM33LMNASLC22A6 | |
| Cyclohexanone SCHEMBL7064054 | 0.86 | FFAR3 (0.56) | ALDH1A1TRIM24TRIM33HSD17B10OR51E2 | |
| Cyclohexanone SCHEMBL11783871 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TRIM24TRIM33LMNAKDM4E | |
| Cyclopentanone SCHEMBL3625536 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TRIM24TRIM33LMNAKDM4E | |
| Cyclohexanone SCHEMBL977979 | 0.84 | ALDH1A1 (0.58) | ALDH1A1TRIM24TRIM33LMNAKDM4E | |
| Cyclohexanone SCHEMBL999716 | 0.83 | TRIM24 (0.73) | ALDH1A1TRIM24TRIM33KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104247088-B | The purposes of resin, resin combination, nonaqueous electrolytic solution secondary battery distance piece and its manufacture method and nonaqueous electrolytic solution secondary battery | 住友化学株式会社 | 2017-03-08 | — | — | CN | disclosed |
| CN-106371163-A | Liquid crystal cured film, optical film including the liquid crystal cured film, and display device | 住友化学株式会社 | 2017-02-01 | — | — | CN | disclosed |
| CN-106371164-A | Laminated body, circularly polarizing plate including laminated body, display device including laminated body | 住友化学株式会社 | 2017-02-01 | — | — | CN | disclosed |
| CN-104271664-B | Resin combination, nonaqueous electrolytic solution secondary battery distance piece and manufacture method thereof and nonaqueous electrolytic solution secondary battery | 住友化学株式会社 | 2016-09-21 | — | — | CN | disclosed |