Cyclohexanone

Cyclohexanone

SCHEMBL977979

CCC(=O)O.O=C1CCCCC1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.58
TRIM24 O15164 2/20 0.58
TRIM33 Q9UPN9 2/20 0.58
FFAR3 O14843 2/20 0.53
GAA P10253 2/20 0.33
POLB P06746 2/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
CYP1A2 P05177 1/20 0.33
LMNA P02545 1/20 0.33
TSHR P16473 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HTT P42858 1/20 0.32
INMT O95050 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
CNR2 P34972 1/20 0.32
KDM4E B2RXH2 1/20 0.32
HSD17B10 Q99714 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentanone SCHEMBL3625536 1.00 ALDH1A1 (0.58) ALDH1A1TRIM24TRIM33FFAR3GAA
Cyclohexanone SCHEMBL11783871 1.00 ALDH1A1 (0.58) ALDH1A1TRIM24TRIM33FFAR3GAA
Cycloheptanone SCHEMBL28260320 0.87 ALDH1A1 (0.55) ALDH1A1TRIM24TRIM33FFAR3GAA
Cyclohexanone SCHEMBL240660 0.87 ALDH1A1 (0.55) ALDH1A1TRIM24TRIM33FFAR3GAA
Cyclohexanone SCHEMBL19973161 0.87 ALDH1A1 (0.55) ALDH1A1TRIM24TRIM33FFAR3GAA
Cyclohexanone SCHEMBL8569524 0.87 TRIM24 (0.55) ALDH1A1TRIM24TRIM33FFAR3GAA
Cyclohexanone SCHEMBL7064054 0.86 FFAR3 (0.56) ALDH1A1TRIM24TRIM33FFAR3HDAC3
Cyclohexanone SCHEMBL28097133 0.85 ALDH1A1 (0.52) ALDH1A1TRIM24TRIM33FFAR3GAA
Propionic Acid SCHEMBL9346906 0.84 FFAR3 (0.53) ALDH1A1TRIM24TRIM33FFAR3GAA
Succinic Acid SCHEMBL28133010 0.84 ALDH1A1 (0.58) ALDH1A1TRIM24TRIM33POLBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438147-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIAL, OPTICAL MATERIAL OBTAINED FROM COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS INC (JP) 2023-06-21 EP disclosed
EP-3351574-B1 POLYMERIZABLE COMPOSITION FOR OPTICAL MATERIALS, OPTICAL MATERIAL OBTAINED FROM SAID COMPOSITION, AND PLASTIC LENS MITSUI CHEMICALS INC (JP) 2022-12-21 EP disclosed
US-11414515-B2 Polymerizable composition for optical material and optical material and plastic lens obtainable from same composition MITSUI CHEMICALS, INC. (JP) 2022-08-16 US disclosed
US-11414429-B2 Compound or pharmaceutically acceptable salt thereof RIKEN (JP) 2022-08-16 US disclosed
US-11358354-B2 Process for producing plastic lens and apparatus for producing plastic lens MITSUI CHEMICALS, INC. (JP) 2022-06-14 US disclosed
EP-3315489-B1 METHOD FOR MANUFACTURING PENTAERYTHRITOL MERCAPTO CARBOXYLIC ACID ESTER, POLYMERIZABLE COMPOSITION, RESIN, OPTICAL MATERIAL, AND LENS MITSUI CHEMICALS INC (JP) 2021-09-22 EP disclosed
EP-3480198-B1 NOVEL COMPOUND OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF RIKEN (JP) 2021-05-05 EP disclosed
US-20210079151-A1 METHOD FOR SETTING POLYMERIZATION CONDITION AND METHOD FOR MANUFACTURING OPTICAL MATERIAL MITSUI CHEMICALS, INC. (JP) 2021-03-18 US disclosed
EP-3778655-A1 METHOD FOR SETTING POLYMERIZATION CONDITIONS AND METHOD FOR PRODUCING OPTICAL MATERIAL Mitsui Chemicals, Inc. (JP) 2021-02-17 EP disclosed
US-10723832-B2 Polymerizable composition for optical material and optical material and plastic lens obtainable from same composition MITSUI CHEMICALS, INC. (JP) 2020-07-28 US disclosed
EP-1690685-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2009-04-15 EP disclosed
US-20080102377-A1 rechargeable batteries having excellent battery cycle properties, electrical capacity and storage characteristic during charging, comprising electrodes and a nonaqueous electrolytic solution containing a dicarbonyl compound as an additive UBE INDUSTRIES, LTD (JP) 2008-05-01 US disclosed
US-20070241313-A1 polymerizing a polymerization raw material in contact with polarizing film; raw material composition contains as one main component an isocyanated or isothiocyanated compound which reacts with the hydroxyl of polyvinyl alcohol resin of polarizing film to form a urethane bond or thiourethane bond SUNLUX CO., LTD. (JP) 2007-10-18 US disclosed
US-20070149562-A1 OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF SANOFI-AVENTIS (FR) 2007-06-28 US disclosed
EP-1739462-A1 POLARIZING PLASTIC OPTICAL DEVICE AND PROCESS FOR PRODUCING THE SAME Sunlux Co., Ltd. (JP) 2007-01-03 EP disclosed
EP-1690685-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2006-08-16 EP disclosed
EP-0553801-B1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS (JP) 1997-04-23 EP disclosed
WO-1997006218-A1 POWDER PAINT COMPOSITION DSM N.V. (NL) 1997-02-20 WO disclosed
US-5389708-A Polymerizing polyisocyanate or polyisothiocyanate with polyol or polythiol in presence of thiophosphoric or dithiophosphoric acid ester MITSUI TOATSU CHEMICALS, INC. (JP) 1995-02-14 US disclosed
EP-0553801-A1 Use of sulfur-containing acid phosphoric ester as internal release agent MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-08-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11414429-B2 Compound or pharmaceutically acceptable salt thereof DPP8, DPP7, AZI2 ALDH1A1 115/4885TRIM24 4022/4885TRIM33 3587/4885
US-20070149562-A1 OXOPIPERIDINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF MC5R, MC4R, OPRD1 ALDH1A1 338/4885TRIM24 2170/4885TRIM33 3862/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.