Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A known ✓ | P29274 | 3/20 | 0.60 |
| ▸ | ADORA2B known ✓ | P29275 | 3/20 | 0.60 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 2/20 | 0.60 |
| ▸ | ADORA1 known ✓ | P30542 | 2/20 | 0.60 |
| ▸ | INMT | O95050 | 4/20 | 0.63 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.59 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.59 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.59 |
| ▸ | GAPDH | P04406 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | STAT6 | P42226 | 1/20 | 0.59 |
| ▸ | PI4KA | P42356 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.59 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenosine SCHEMBL225269 | 0.99 | INMT (0.61) | INMTADORA2AADORA2BADORA3ADORA1 | |
| Adenosine SCHEMBL225271 | 0.99 | INMT (0.61) | INMTADORA2AADORA2BADORA3ADORA1 | |
| Inosine SCHEMBL8836252 | 0.92 | ADORA2A (0.55) | INMTADORA2AADORA2BADORA3ADORA1 | |
| Adenosine Phosphate SCHEMBL2037385 | 0.89 | P2RY1 (0.65) | INMTADORA1SMN1; SMN2 | |
| Adenosine Phosphate SCHEMBL15670577 | 0.89 | P2RY1 (0.65) | INMTADORA1SMN1; SMN2 | |
| SCHEMBL11772880 | 0.88 | MARS1 (0.62) | INMTADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL225270 | 0.88 | MARS1 (0.62) | INMTADORA2AADORA2BADORA3ADORA1 | |
| Guanosine SCHEMBL11034252 | 0.85 | HINT1 (0.66) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL21067651 | 0.84 | P2RY1 (0.60) | INMTADORA1SMN1; SMN2 | |
| Adenosine Phosphate SCHEMBL15670433 | 0.83 | P2RY1 (0.58) | INMTADORA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106467743-B | The gold nanoclusters and its preparation method and application of high temperature resistant luminescence enhancement | 东南大学 | 2018-09-21 | — | — | CN | disclosed |
| CN-106467743-A | Gold nanoclusters of high temperature resistant luminescence enhancement and its preparation method and application | 东南大学 | 2017-03-01 | — | — | CN | disclosed |